Optimizing Clinical Studies Recruitment

Effective Trial Design - historical control use / everyone gets the drug

Given that there have been over 20 phase 3 disease modifying trials in the past / open currently, we should encourage sponsors to start using pooled data from their historical controls in Phase III trials so that all patients in the next generation of AD trials have access to the investigational drug. If all participants receive the drug, there would be less barriers caused by patients feeling that they may be wasting their time and are receiving a placebo



5 votes
Idea No. 311