Test models that move clinical research from the site to the community to lower barriers for volunteering. Consider use of mobile units, home or other residential settings, online assessments, satellite offices, and telemedicine, and seek flexibility from the study sponsors or health authorities.
Cultivating Recruitment Science
What research questions do we need to answer about recruitment?
To continue to enhance effectiveness of recruitment efforts and improve tools, research methods, and recruitment practices, it is critical that we build the evidence base for a "science of recruitment." This evidence base can build the case for proven recruitment techniques and guide future study design, recruitment plans, and decision-making.
Ideas in this area might address:
- Identifying and characterizing target audiences
- Developing and testing audience-specific strategies and tactics
- Identifying gaps in knowledge about recruitment strategies and implementation
- Evaluating recruitment strategy success
- Developing a robust evidence base for recruitment strategies and a science of recruitment
Stress the early screening available and possible early medication to slow the disease. Many people want to dismiss their symptoms ad lose time for treatment to get staryed.
The testing that is available presently is for identify mild, moderate, or advanced ALZ. There have recently been limited research to see if the sooner a person is identified and treatment begins the slower the disease progresses.
Need research to develop tests to identify earlier symptoms of the disease.
Assess clinicians’ knowledge, interest and hesitance in telling patients about or referring them to clinical studies, generally and specifically for dementia.
Steps: 1) Identify salient beliefs, attitudes, values, and perceived behavioral norms and/or incentives (monetary and non-monetary) likely to affect whether people in various audiences are motivated – or not -- to join in research. 2) Articulate major barriers to participation in dementia research in each audience segment, especially among underrepresented groups. 3) Find out what key influencers, such as disease advocates, ...more »
1) Identify target audiences for messaging and incentives related to recruitment to clinical trials and long-term natural history studies. This includes primary audiences of potential participants, as well as secondary groups and influencers, such as caregivers and clinicians, who can support recruitment and retention. 2) Determine each target audience’s current knowledge and predispositions regarding participation in ...more »
Assess the state of the field, with respect to current approaches, modalities, space, and performance. Look at registries in the context of their utility for recruitment to small studies as well as for large multi-site trials and national surveys. Identify best practices in recruiting and retaining registry volunteers for prolonged periods.
It strikes me that recruiting for trials is very similar to the process used to market any product or service. I really recommend engaging a strong marketing partner. It's all about the funnel. First, identifying the target market (who do we want to recruit), then determining how to best reach them. In order to get one person out the end of the funnel (meaning into a clinical study), how many need to be "interested" ...more »
With each successful clinical study recruitment effort, the lessons learned should be added to a national list of best practices. The same goes for unsuccessful recruitment efforts in discovering what did not work and why. These best practices must be shared online in a way that is easily searchable (e.g. recruitment promotion, study materials, phone screening, etc.) so that study teams can create their plan using the ...more »
Explore how the “Internet of Things,” with its sensory technologies, augmented reality, and machine-learning algorithms might be used to understand the personal needs of each research participant and to optimize engagement in research activities.
Test, whenever possible, the effectiveness of messaging and incentives for participation for varying audiences (patients, study partners and clinicians, specifically) and study types (e.g. dementia vs. prevention trials). Evaluate the relative advantages and disadvantages of different strategies on motivation and action toward research participation.
Assess the use of social networks, crowd sourcing and other digital environments, like disease forums, that would facilitate “pre-recruitment” discussions about the state of the science related to Alzheimer’s, improving awareness and inspiring curiosity about registries or clinical studies.
Examine the motivators, barriers, and facilitators to enrolling and remaining in a registry until invited to be considered for a study. Identify methods that influence a registry enrollee to participate in a study, including an analysis of how participants’ cognitive and functional status, demographics and other variables influence their registry behavior.
Invest in site specific outreach campaigns to GPs and specialists in the vicinity of a clinical trial site for generating awareness and to promote referral from the clinical setting.
Just like we see in drug stores and some big box stores what about a chair with a touch screen? The participant sits down, accepts the terms, and begins the test. It could be a condensed set of questions that screen for early signs of cognitive decline with a score at the end. The constraints could regard age, or showing ID to a pharmacist first without having to enter identifying information in the "data chair". A ...more »