(@localdiversegrp)

Building Relationships with Local Communities

Community education and training

Train and certify champions to discuss clinical trials and research within communities. Create a bureau of speakers, ideally well-suited to cultural needs of the local community, to provide community education and training for clinicians and other healthcare providers. Ensure that messaging is culturally and linguistically appropriate for targeted audience, as similar language may be interpreted radically differently ...more »

Voting

8 votes
(@vraghavan)

Optimizing Clinical Studies Recruitment

Effective Trial Design - historical control use / everyone gets the drug

Given that there have been over 20 phase 3 disease modifying trials in the past / open currently, we should encourage sponsors to start using pooled data from their historical controls in Phase III trials so that all patients in the next generation of AD trials have access to the investigational drug. If all participants receive the drug, there would be less barriers caused by patients feeling that they may be wasting ...more »

Voting

5 votes

Building Relationships with Local Communities

Better utilize partner organizations and social media

Most studies appear to require participants to live geographically near a study site. This should allow the leveraging of local partner organizations to get the word out to their constituents via email and social media. These partner organizations could range, for example, from United Way to religious institutions (churches, mosques, temples, etc), community groups, non-profits (museums, food banks, etc.), and even small ...more »

Voting

5 votes

Cultivating Recruitment Science

Alzheimer's Research in Action

Many people have no clue what it means to participate in a research study. As we age, we learn by doing. The best way to get buy in from the community is to walk them through the stages of actual research. A small group would be terecruited to move through the different phases of the proposed research in an open forum.

Voting

6 votes
(@hjohnson)

Optimizing Clinical Studies Recruitment

Educate and Screen Same Day

I piloted an event in which I partnered with a research entity that was recruiting. The event started with "education" over the course of an hour. People were engaged and awareness was absorbed by many in the room. Following the "educational" portion the research entity offered private screenings on site. The appointment slots were full, with many people wanting the research entity to come back the next day. While ...more »

Voting

28 votes
(@geraldktzm)

Optimizing Clinical Studies Recruitment

Optimizing Involvement and Recruitment of Subjects for Clinical Studies

My wife died of early onset Alzheimer's Disease. In looking at potential studies, it was clear that we would not be provided results. This was particularly distressing for the genetic studies, since I have three children who could also be afflicted with the disease, should it have a hereditary basis. I am sure that a legal document could be drafted to free investigators from liability. In this manner, subjects and ...more »

Voting

32 votes

Optimizing Clinical Studies Recruitment

Brainpaths as a Potential Treatment for Cognitive Impairment in Aging

The development of novel therapeutic strategies for Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) are major critical goals for neuroscience. Much attention has been given to the development of disease modifying pharmacological strategies targeting a-Beta and/or p-tau accumulation, but to date, all relevant clinical trials have failed. This had led to a resurgence of interest in the development of tools ...more »

Voting

13 votes

Optimizing Clinical Studies Recruitment

Make the Recruitment and Retention plan an intrinsic part of the study's methodology

My humble opinion is to make the Recruitment and Retention plan an intrinsic part of the study's methodology. It is important to perhaps run focus groups prior to developing this phase both with the potential participants, and also with their service providers. We need to take into account not only a participant's race, ethnicity, SES, culture in general, but also historical factors, and their ideas and stigmas about ...more »

Voting

8 votes
(@eterril)

Raising Awareness

Reach Out to Religious Groups

Form a plan to reach out to religious groups. Often these groups comprise altruistic, compassionate persons who want to make a difference in their communities and world, and who want to support organizations that also have that aim. Ask to speak to interfaith groups such as local Ministerial Alliance and Church Women United meetings. Ask to speak to individual denominational meetings (although I suspect the interfaith ...more »

Voting

6 votes