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Invest in site specific outreach campaigns to GPs and specialists in the vicinity of a clinical trial site for generating awareness and to promote referral from the clinical setting.
Raise awareness on the importance of brain health through celebrity driven awareness campaigns. Much like the Selena Gomez campaign on Lupus nephritiis, institute a celebrity driven campaign for AD targeted towards the 50+ population
Set up a newspaper based advertisement with regular frequency in a section that targets the 50+ population to raise awareness on the importance of brainhealth.
For patients and physicians who register with an online patient registry, the registry should automatically send weekly updates on new trials open close to the zip code of the patient or the physician so that the stakeholder can be informed of new trials through a more passive approach
Build guidelines for referral of patients to clinical trials / educate specialists to think about AD clinical trials as an attractive treatment option for their patients. If this is well instituted, physicians will bring up clinical trial participation in conversation during visits, which would spark a conversation gauging the interest of a patient to participate in a CT.
Provide monetary incentives to neurologists and specialists who refer patients to a clinical trial. If sponsors monetarily incentivize neurologists, and get the word out to community specialists near trial sites conducting AD trials, to increase trial referrals from their practice, thereby fastening recruitment.
Increase the placebo to experimental drug arm ratio in such a way that a larger proportion of patients recieve the investigational compound. This would make the trial a lot more attractive.
Given that there have been over 20 phase 3 disease modifying trials in the past / open currently, we should encourage sponsors to start using pooled data from their historical controls in Phase III trials so that all patients in the next generation of AD trials have access to the investigational drug. If all participants receive the drug, there would be less barriers caused by patients feeling that they may be wasting ...more »
Institute a celebrity driven awareness campaign targeted towards raising awareness of clinical trials in AD among the 50+ age cohort either through TV ads or on the radio or through newspapers.